Let us understand 3 components commonly used in SPD.
Transient voltage suppressors:They are based on avalanche diodes and zener diodes. Diodes are made of semiconductors usually silicon, at a junction between n and p doped regions. TVS devices provide protection with combination of forward bias and reverse bias breakdown conduction.
MOV (Metal Oxide varistor) : Varistors are usually made of ceramic of zinc oxide grains in a matrix of other oxides. The grains form diodes with surrounding matrix, creating a complex array of parallel and anti-parallel diodes. At higher voltages, the individual diodes begin to conduct and the resistance of the varistor drops dramatically.
Gas Discharge Tubes: They are usually formed with ceramic body filled with gas mixture containing neon and argon and two or more electrodes. When voltage across the electrodes exceeds a specified value an arc occurs within the tube which provides low current path.
Following table mentions difference between these components.
 
Type  | 
   Speed  | 
   Accuracy  | 
   Current capability  | 
   Lowest crowbar trigger voltage  | 
   Wearout  | 
  
Gas Discharge Tube (GDT)  | 
   Slow  | 
   Fair  | 
   High  | 
   75 V  | 
   Will fail after numerous stresses depending on severity.  | 
  
Transient Voltage Suppressor (TVS)  | 
   Fast  | 
   Good  | 
   Low  | 
   NA  | 
   NO  | 
  
Metal Oxide Varistor (MOV)  | 
   Fair  | 
   Poor  | 
   Medium  | 
   NA  | 
   Yes  |